![]() ![]() Its etiology and pathogenesis are not well established however, it is believed to be triggered by placental hormones. Gestational gigantomastia was first described in 1648 by Palmuth. The decision to presenting this case report was made after receiving written and oral consent from our patient. The patient’s follow-up went smoothly and she was discharged after post-natal reconstructive surgery was scheduled. ![]() The histopathologic evaluation of the specimen revealed marked lactation changes of the epithelial component and increased vascularization in the stroma. On 6 th postoperative day, surgical debridement was performed for necrosis that had developed on the left areola and parts of skin. The measurements of the excised tissue from the right and left breasts were 3750 gr and 3700 gr, respectively. Therefore, the reconstruction was postponed to another session. However, the operation was finalized after completion of bilateral subcutaneous mastectomy due to acute hemorrhage causing hemodynamic instability and severe anemia (intraoperative hemoglobin 5.7 11.2 g/dL). At the 24 th gestational week, the patient was scheduled bilateral subcutaneous mastectomy and implant placement. Breast ultrasonographic examination revealed diffuse hypoechoic areas with increased vascularity there were no subcutaneous fat planes or solid/cystic masses in either breast. The patient weighed 75 kg and was 165 cm in height, with a body mass index (BMI) of 28 kg/m 2. Additionally, the patient had back pain, difficulty in movement, and difficulty in meeting daily needs. Physical examination findings were extreme growth in both breasts, distinct subcutaneous venous structures, and some necrotic areas on the skin ( Figure 1). She noticed excessive and rapid breast growth after the 14 th week of pregnancy there was no family history of a similar condition. The patient was in her third pregnancy and had experienced breast growth within physiologic limits in her previous pregnancies. A pregnant woman aged 26 years with no apparent systemic disease and medication history who was 22 weeks pregnant was admitted to our breast surgery outpatient clinic because of rapid growth in both breasts, which caused back pain, and difficulty in movement. ![]()
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